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About Us

TOP Workplaces Award Winner

Purpose-driven work. Real patient impact.

Every breakthrough begins with exceptional people who are passionate about improving patient care. At Castle, you’ll find a people-first culture where collaboration, growth and meaningful work come together to make a difference for patients every day. Explore open positions and discover your future with the Castle team.

At Castle, it all comes down to people. After all, disease doesn’t just happen — it happens to people. We believe that disease management and treatment decisions can be better informed through a person’s unique biology, which is revealed through the scientific rigor of our innovative tests. We are committed to empowering healthcare providers and patients with the goal of improved outcomes.

Every employee at Castle has an impact on patient care, and we work to ensure that everyone finds their work to be both challenging and rewarding. We behave with integrity and treat our colleagues with respect and kindness. Our culture fosters an environment of trust, transparency, and collaboration. We prioritize and encourage internal growth and professional development.

Castle Biosciences is an equal opportunity employer as to all protected groups, including protected veterans and individuals with disabilities.

If you have a disability and you believe you need a reasonable accommodation in order to search for a job opening or to submit an online application, please e-mail ReasonableAccommodationsRequest@castlebiosciences.com.

Latest Jobs

Castle Biosciences Inc. is growing, and we are looking to hire an IT, Facility & Operations Analyst working from our Pittsburgh, PA office location with a start date on or before November 1, 2026. Why Castle Bioscien...
2d ago
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Learn more at www.CastleBiosciences.com Castle Biosciences Inc. is growing, and we are looking to hire a full-time SharePoint Administrator & IT Specialist working from our headquarters in Friendswood, TX. with a sta...
2d ago
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Castle Biosciences Earns "Top Workplaces USA Award" for Phoenix, Pittsburgh, and Friendswood! Learn more at www.CastleBiosciences.com Castle Biosciences Inc. is growing, and we are looking to hire a full-time Clinical Re...
3w ago
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